1-Methylpiperidine-4-carboxylic acid

CAS: 68947-43-3

Ref. 3D-FM61568

Product Information

• Name: 1-Methylpiperidine-4-carboxylic acid
• Synonyms: 1-Methyl-4-piperidinecarboxylic acid, 4-Piperidinecarboxylic Acid, 1-Methyl-, N-Methylisonipecotic acid, T6Ntj A1 Dvq, 1-Methylpiperidine-4-Carboxylic Acid, 1-Methyl-Piperidine-4-carboxylic acid

Description

1-Methylpiperidine-4-carboxylic acid is a potent inhibitor of acetylcholinesterase and butyrylcholinesterase, which are enzymes that break down the neurotransmitter acetylcholine. It is used to treat myasthenia gravis, a condition in which the body's immune system attacks the neuromuscular junction, causing muscle weakness. 1-Methylpiperidine-4-carboxylic acid was shown to be selective for nicotinic receptors, with no effect on muscarinic receptors. This is believed to be due to steric interactions between the two molecules. 1-Methylpiperidine-4-carboxylic acid is an acidic compound that undergoes hydrolysis under basic conditions. It can react with amines to form imine derivatives that are also acidic compounds.

• Brand: Biosynth

Chemical properties

• Molecular weight: 143.18 g/mol
• Formula: C₇H₁₃NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C7H13NO2/c1-8-4-2-6(3-5-8)7(9)10/h6H,2-5H2,1H3,(H,9,10)
• InChI key: InChIKey=HCKNAJXCHMACDN-UHFFFAOYSA-N
• SMILES: CN1CCC(C(=O)O)CC1