trans-4-Methoxy-β-nitrostyrene

CAS: 3179-10-0

Ref. 3D-FM67975

Product Information

• Name: trans-4-Methoxy-β-nitrostyrene
• Synonyms: 1-(4-Methoxyphenyl)-2-nitroethene, 1-Methoxy-4-(2-nitroethenyl)benzene, 1-Methoxy-4-(2-nitrovinyl)benzene, 1-Nitro-2-(4-methoxyphenyl)ethene, 1-methoxy-4-[(E)-2-nitroethenyl]benzene, 2-(4-Methoxyphenyl)-1-nitroethene, 2-(4-Methoxyphenyl)nitroethylene, 4-(2-Nitrovinyl)anisole, 4-Methoxy-β-nitrostyrene, 4-Methoxy-ω-nitrostyrene, Anisole, p-(2-nitrovinyl)-, Benzene, 1-methoxy-4-(2-nitroethenyl)-, Chembridge 5102117, Methoxywnitrostyrene, NSC 23856, p-(2-Nitrovinyl)anisole, p-Methoxy-β-nitrostyrene, β-Nitro-4-methoxystyrene

Description

Trans-4-Methoxy-beta-nitrostyrene is a chiral, catalytic compound that was synthesized from 4-methoxybenzaldehyde and nitrous acid. It has been shown to inhibit the growth of rat thoracic 5-hydroxytryptamine (5-HT)1A receptor neurons and prevent the activation of these receptors by serotonin in rats. Trans-4-Methoxy-beta-nitrostyrene may have therapeutic potential as an antidepressant or antiemetic drug. The mechanism of action is not fully understood, but it is thought that trans-4-Methoxy-beta-nitrostyrene binds to the active site on the 5HT1A receptor and blocks serotonin binding. Trans-4 Methoxy beta nitrostyrene has also been shown to inhibit folic acid synthesis in cancer cells, which may be due to its ability to inhibit methionine synthase through amines.

• Brand: Biosynth

Chemical properties

• Molecular weight: 179.17 g/mol
• Formula: C₉H₉NO₃
• Purity: Min. 98 Area-%
• Color/Form: Powder