Product Information
Methyl 2-acetylbenzoate is a chiral β-unsaturated ketone that can be synthesized by the reaction of methyl acetoacetate with boron trifluoride diethyl etherate. It has been used as a drug molecule and in the synthesis of other drugs. Methyl 2-acetylbenzoate was prepared by asymmetric catalytic hydrogenation of methyl 2-methylpropionate, which is an enolate anion. The enolate anion attacks the electrophilic carbon atom (c-h bond) on the malonate, resulting in nucleophilic attack and formation of a new covalent bond. This reaction takes place at elevated temperatures. This compound is widely used for the synthesis of other drugs, such as antihypertensive agents and anticonvulsants.
Chemical properties
Technical inquiry about: 3D-FM71992 Methyl 2-acetylbenzoate
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