2-Methyl-8-nitroquinoline

CAS: 881-07-2

Ref. 3D-FM75583

Product Information

• Name: 2-Methyl-8-nitroquinoline
• Synonyms: 8-Nitro-2-methylquinoline, NSC 163380, Nitroquinaldine, Quinaldine, 8-nitro-, Quinoline, 2-methyl-8-nitro-, 8-Nitroquinaldine

Description

2-Methyl-8-nitroquinoline (2MNQ) is a leukotriene receptor antagonist that prevents the binding of leukotrienes to their receptors, thereby inhibiting their effects. 2MNQ has been shown to be effective in treating virulent infections, such as MRSA and Pseudomonas aeruginosa. 2MNQ can be used in a dry weight assay for measuring the inhibition of leukotriene receptors. The interaction of 2MNQ with leukotriene receptors is specific, which makes it important for elucidating the mechanism of action. A homogeneous assay using biphenyl as a substrate for 2MNQ is also available for measuring its inhibitory activity on leukotriene receptors.
2MNQ binds to flavins and hydrochloric acid in an inorganic manner and has a redox potential that is low enough to allow efficient reaction with hydrogen peroxide or an organic base.

• Brand: Biosynth

Chemical properties

• Molecular weight: 188.18 g/mol
• Formula: C₁₀H₈N₂O₂
• Purity: Min. 95%