4-Methylphenyl Trifluoromethanesulfonate
CAS: 29540-83-8
Ref. 3D-FM85482
| 1g | To inquire | |
| 5g | To inquire | |
| 500mg | To inquire |
Product Information
The reaction of 4-methylphenyl trifluoromethanesulfonate with aryl Grignard reagents provides an efficient route to the synthesis of chiral organic compounds. The reaction proceeds in high yield and with excellent stereoselectivity. The mechanism involves Pd-catalyzed coupling of the electrophilic methyl group on the sulfonate with a nucleophilic carbon atom on the Grignard reagent. This process is thought to proceed through a sequence of steps including hydroxy group activation, acyl transfer, and elimination.
Chemical properties
Technical inquiry about: 3D-FM85482 4-Methylphenyl Trifluoromethanesulfonate
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