Product Information
- 1-(2-Methylpropyl)-1H-1,3-benzodiazole
- 1-(2-Methylpropyl)-1H-benzimidazole
- 1-Isobutylbenzimidazole
- 1H-Benzimidazole,1-(2-methylpropyl)-(9CI)
- 1H-Benzimidazole, 1-(2-methylpropyl)-
1-Isobutyl-1H-benzimidazole is a potent and selective inhibitor of cell proliferation. It inhibits the growth of cancer cells by targeting the catalytic activity of topoisomerase II. The in vitro cytotoxic activity of 1-isobutyl-1H-benzimidazole has been investigated on human cancer cells and endometrial cancer cells. The IC50 values for cisplatin, a chemotherapeutic agent, and 1-isobutyl-1H-benzimidazole were found to be identical at 10 μM. Endometrial cancer cells were more sensitive to 1-isobutyl-1H-benzimidazole than human cancer cells.
Chemical properties
Technical inquiry about: 3D-FMA34688 1-Isobutyl-1H-benzimidazole
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