Nuclear Factor NF-KB Inhibitor SN50 trifluoroacetate salt

CAS: 213546-53-3

Ref. 3D-FN109704

Product Information

• Name: Nuclear Factor NF-KB Inhibitor SN50 trifluoroacetate salt
• Synonyms: H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln- Arg-Lys-Arg-Gln-Lys-Leu-Met-Pro-OH H-AAVALLPAVLLALLAPVQR KRQKLMP-OH, 1: PN: WO2009039966 PAGE: 99 claimed protein, 20: PN:WO2005013886 SEQID: 20 unclaimed protein, 20: PN: WO2005042719 SEQID: 4unclaimed protein, 23: PN: WO2004039957 SEQID: 23 unclaimed protein, 45: PN: US20060040879 SEQID: 45 claimed protein, 5: PN: WO02094185 SEQID: 15 unclaimed protein, 69: PN:WO2005081911 SEQID: 6 claimed protein, 74: PN: WO2006109196 SEQID: 74 unclaimedsequence, PN: US5962415 SEQID: 5 claimed protein, Sn 50, SN 50 (enzymeinhibitor)
• CAS: 213546-53-3

Description

SN50 is a nuclear factor NF-KB inhibitor that blocks the activity of transcription factors that are involved in inflammation and cancer. SN50 inhibits protease activity, which may be due to its ability to bind to response elements on DNA, leading to cytosolic calcium release and activation of signal pathways. It also binds to endothelin-a receptor and induces apoptosis. SN50 has been shown to have anti-tumour effects in resistant breast cancer cells as well as reducing serum aminotransferase levels in rats. This drug also activates transcriptional regulation by binding toll-like receptors and inducing colony stimulating factors. SN50 also has cardioprotective properties, which may be due to its ability to inhibit fatty acid synthase in cardiomyocytes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 2,781.5 g/mol
• Formula: C₁₂₉H₂₃₀N₃₆O₂₉S
• Purity: Min. 95%