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Necrostatin-1 5-(1
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Necrostatin-1 5-(1

CAS: 4311-88-0

Ref. 3D-FN111188

10mg
317.00 €
25mg
529.00 €
50mg
878.00 €
100mg
1,405.00 €
250mg
3,053.00 €
Estimated delivery in United States, on Monday 15 Jul 2024

Product Information

Name:
Necrostatin-1 5-(1
Synonyms:
  • H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone
  • MTH-DL-Tryptophan Methylthiohydantoin-DL-tryptophan
  • 5-(1H-indol-3-ylmethyl)-3-methyl-2-thioxoimidazolidin-4-one
  • Necrostatin-1
  • 5-(1H-Indol-3-Ylmethyl)-3-Methyl-2-Thioxo-4-Imidazolidinone
Description:

Necrostatin-1 is a small molecule inhibitor that blocks the NF-κB signaling pathway. Necrostatin-1 is a potent inducer of apoptosis and has been shown to inhibit necroptosis in cell culture. It also blocks the Toll-like receptor 4 (TLR4), which is an important death receptor that causes inflammation. Necrostatin-1 has been found to be effective in reducing injury and death in low doses, but has not been tested for long periods of time or at high doses.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
259.33 g/mol
Formula:
C13H13N3OS
Purity:
Min. 95%
InChI:
InChI=1S/C13H13N3OS/c1-16-12(17)11(15-13(16)18)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,14H,6H2,1H3,(H,15,18)
InChI key:
InChIKey=TXUWMXQFNYDOEZ-UHFFFAOYSA-N
SMILES:
CN1C(=O)C(Cc2c[nH]c3ccccc23)NC1=S
MDL:
Melting point:
Boiling point:
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Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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