NLG919

CAS: 1402836-58-1

Ref. 3D-FN137701

Product Information

• Name: NLG919

Description

NLG919 is a small molecule that inhibits the enzyme IDO1, which is responsible for the breakdown of tryptophan. This inhibition results in increased levels of tryptophan and increased production of tumor necrosis factor-α (TNF-α), which has been shown to have significant cytotoxicity on prostate cancer cells. NLG919 also has potential to be an immunotherapy agent, as it induces antibodies against tumor cells. The proposed mechanism of action for NLG919 is based on its ability to inhibit IDO1 and TNF-α production, which can lead to tumor regression.

• Brand: Biosynth

Chemical properties

• Molecular weight: 282.38 g/mol
• Formula: C₁₈H₂₂N₂O
• Purity: Min. 95%
• Color/Form: Solid
• InChI: InChI=1S/C18H22N2O/c21-18(13-6-2-1-3-7-13)10-16-14-8-4-5-9-15(14)17-11-19-12-20(16)17/h4-5,8-9,11-13,16,18,21H,1-3,6-7,10H2
• InChI key: InChIKey=YTRRAUACYORZLX-UHFFFAOYSA-N
• SMILES: OC(CC1c2ccccc2-c2cncn21)C1CCCCC1