5-NITROOROTIC ACID
CAS: 17687-24-0
Ref. 3D-FN153816
| 1g | Discontinued | ||
| 2g | Discontinued | ||
| 100mg | Discontinued | ||
| 250mg | Discontinued | ||
| 500mg | Discontinued |
Product Information
Name:
5-NITROOROTIC ACID
Synonyms:
- 1,2,3,6-Tetrahydro-5-nitro-2,6-dioxo-4-pyrimidinecarboxylic acid
- 2,6-Dihydroxy-5-nitropyrimidine-4-carboxylic acid
- 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-5-nitro-2,6-dioxo-
- 5-Nitro-2,6-Dioxo-1,2,3,6-Tetrahydropyrimidine-4-Carboxylic Acid
- 5-Nitroorotic acid
- 5-Nitrouracil-6-carboxylic acid
- 6-Nitro-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylic Acid
- NSC 43248
- Orotic acid, 5-nitro-
- 1,2,3,6-Tetrahydro-5-nitro-2,6-dioxopyrimidine-4-carboxylic acid
- See more synonyms
Description:
5-Nitroorotic acid (5NOA) is a pyrimidine derivative that inhibits protein synthesis. It acts as a competitive inhibitor of the enzyme, orotic aciduria, which converts orotidine 5′-monophosphate to uridine monophosphate. Orotic aciduria is one of the enzymes in the pathway for the synthesis of pyrimidines and purines. This compound has been shown to inhibit the enzyme by binding to its active site and forming a stable complex with it. The inhibition of this enzyme leads to an accumulation of orotic acid and deoxyribonucleotides in cells, causing cellular death.
Notice:
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
201.09 g/mol
Formula:
C5H3N3O6
Purity:
Min. 95%
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HS code:
