Nafcillin

CAS: 147-52-4

Ref. 3D-FN170647

Product Information

• Name: Nafcillin
• Synonyms: (2-Ethoxy-1-naphthyl)penicillin, (2S,5R,6R)-6-[[(2-Ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, (2S,5R,6R)-6-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))-, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-ethoxy-1-naphthamido)-3,3-dimethyl-7-oxo-, 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-, 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, [2S-(2α,5α,6β)]-, 6-(2-Ethoxy-1-naphthamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, Brn 0862393, Hsdb 3133, Nafcilin-1, Nafcilina, Nafcilina [INN-Spanish], Nafcilline, Nafcilline [INN-French], Nafcillinum, Nafcillinum [INN-Latin], Nallpen, Naphcillin, Penicillin, (2-ethoxy-1-naphthalenyl)-, Penicillin, (2-ethoxy-1-naphthyl)-, Unii-4Cnz27M7Rv, sodium (5R,6R)-6-[(2-ethoxynaphthalen-1-yl)carbamoyl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

Description

Nafcillin is a bactericidal antibiotic that inhibits bacterial cell wall synthesis. It binds to the penicillin-binding protein, which prevents the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. Nafcillin has been shown to have a concentration-time curve that increases linearly in streptococcal pharyngitis infections. The effective concentration is 100 mg/L, but it does not have any effect on infectious diseases caused by gram-negative bacteria. Vancomycin therapy can be used to treat these infections.

• Brand: Biosynth

Chemical properties

• Molecular weight: 414.48 g/mol
• Formula: C₂₁H₂₂N₂O₅S
• Purity: Min. 95%
• Color/Form: Solid