Naphthalene-1-sulfonamide

CAS: 606-25-7

Ref. 3D-FN176411

Product Information

• Name: Naphthalene-1-sulfonamide
• Synonyms: α-Naphthalenesulfonamide, 1-Naphthylsulfonamide, 1-Naphthalenesulfonamide

Description

Naphthalene-1-sulfonamide is a growth factor that inhibits the activity of cyclic nucleotide phosphodiesterase. It has been shown to have antiproliferative effects in cancer cells, but its effect on non-cancerous cells is unknown. Naphthalene-1-sulfonamide binds to the active site of cyclic nucleotide phosphodiesterase, which may inhibit the hydrolysis of cAMP and ATP. The binding of naphthalene-1-sulfonamide to cyclic nucleotide phosphodiesterase may also result in an increase in intracellular levels of cAMP and ATP, leading to inhibition of protein kinase A and D activity. This can lead to decreased cellular proliferation, increased apoptosis, or both.

• Brand: Biosynth

Chemical properties

• Molecular weight: 207.25 g/mol
• Formula: C₁₀H₉NO₂S
• Purity: Min. 95%
• InChI: InChI=1S/C10H9NO2S/c11-14(12,13)10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,(H2,11,12,13)
• InChI key: InChIKey=ZFIFHAKCBWOSRN-UHFFFAOYSA-N
• SMILES: NS(=O)(=O)c1cccc2ccccc12