N-(NBD-aminohexanoyl) D-erythro-sphingosine

CAS: 94885-02-6

Ref. 3D-FN26168

Product Information

• Name: N-(NBD-aminohexanoyl) D-erythro-sphingosine
• Synonyms: N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanamideN-[(7-Nitrobenz-2 -oxa-1,3-diazol-4-yl)aminocaproyl]sphingosineNBD-C 6Cer
• CAS: 94885-02-6

Description

N-(NBD-aminohexanoyl) D-erythro-sphingosine is a fluorescent derivative of the natural sphingolipid, sphingosine. It binds to the cytosolic calcium ion channel, which is responsible for regulating the concentration of calcium ions in cells. The binding of N-(NBD-aminohexanoyl) D-erythro-sphingosine to the cytosolic calcium ion channel inhibits its activity and causes an increase in cytosolic calcium concentrations. This leads to a reduction in cellular proliferation and an increase in cell death by apoptosis. N-(NBD-aminohexanoyl) D-erythro-sphingosine has been shown to inhibit tumor growth and induce cancer cell death by apoptosis via inhibition of protein synthesis and DNA synthesis. The binding properties of N-(NBD-aminohexanoyl) D-erythro-sphingosine have also been

• Brand: Biosynth

Chemical properties

• Molecular weight: 575.74 g/mol
• Formula: C₃₀H₄₉N₅O₆
• Purity: Min. 95%
• Color/Form: Reddish brown solid.