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N-Nitroso-di-n-butylamine
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N-Nitroso-di-n-butylamine

CAS: 924-16-3

Ref. 3D-FN26364

2g
70.00 €
5g
107.00 €
10g
153.00 €
25g
258.00 €
50g
403.00 €
Estimated delivery in United States, on Monday 22 Jul 2024

Product Information

Name:
N-Nitroso-di-n-butylamine
Synonyms:
  • DibutylnitrosamineNDBANSC 6830
Description:

N-Nitroso-di-n-butylamine is a nitrosamine that is a product of wastewater treatment. It has been shown to inhibit mitochondrial function and induce liver lesions in rats at high doses. N-Nitroso-di-n-butylamine is structurally similar to the natural substrate ribose, which leads to inhibition of xanthine oxidase, an enzyme involved in purine metabolism. The structural analysis revealed the presence of reactive sites that are susceptible to attack by nucleophiles, such as hydroxyl radicals or hydrogen peroxide. This indicates that N-Nitroso-di-n-butylamine may be a precursor for other carcinogenic compounds. NADH is reduced by NADH dehydrogenase (complex I) in mitochondria to produce NAD+, which subsequently donates electrons to the electron transport chain and generates ATP. The ability of NNDB to inhibit complex I activity was assessed using hl60

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
158.24 g/mol
Formula:
C8H18N2O
Purity:
Min. 95%
InChI:
InChI=1S/C8H18N2O/c1-3-5-7-10(9-11)8-6-4-2/h3-8H2,1-2H3
InChI key:
InChIKey=YGJHZCLPZAZIHH-UHFFFAOYSA-N
SMILES:
CCCCN(CCCC)N=O
MDL:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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