Product Information
- 1H-Indole-2,3-dione, 6,7-dichloro-, 3-oxime
- 6,7-Dichloro-1H-indole-2,3-dione 3-oxime
- 6,7-Dichloroisatin 3-oxime
- Indole-2,3-dione, 6,7-dichloro-, 3-oxime
- Ns 309
- Ns309
NS309 is a new pharmacological agent that belongs to the group of channel blockers. It inhibits the low-voltage activated calcium channels (LVAcc), which are involved in the regulation of neuronal death. The inhibition of these channels leads to a reduction of cytosolic Ca2+, mitochondrial membrane potential, and mesenteric vasoconstriction. NS309 has been shown to be effective against experimental models of vascular diseases, including high resistance and endothelial dysfunction.
Chemical properties
Technical inquiry about: 3D-FN41091 NS309
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