Z-L-norvaline

CAS: 21691-44-1

Ref. 3D-FN47298

Product Information

• Name: Z-L-norvaline
• Synonyms: Z-L-Nva-OH, (2S)-2-(Phenylmethoxycarbonylamino)pentanoic acid, (Benzyloxycarbonyl)norvaline, <span class="text-smallcaps">L</span>-(Carbobenzyloxy)norvaline, <span class="text-smallcaps">L</span>-Norvaline, N-[(phenylmethoxy)carbonyl]-, CBZ-L-norvaline, Cbz-<span class="text-smallcaps">L</span>-norvaline, Cbz-Norvaline, N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-norvaline, N-(Benzyloxycarbonyl)norvaline, N-(Carbobenzoxy)norvaline, N-Carbobenzyloxy-<span class="text-smallcaps">L</span>-norvaline, N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-norvaline, N-[(benzyloxy)carbonyl]-L-norvaline, Norvaline, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">L</span>-, Z-<span class="text-smallcaps">L</span>-Norvaline

Description

Z-L-Norvaline is a homogeneous, undecapeptide that has been synthesized from the condensation of L-Valine with D-Lysine. Cyclosporin A is a cyclic peptide consisting of ten amino acids. The synthesis of Z-L-norvaline is achieved by the stepwise conversion of cyclosporin A to its subfragments, which are then condensed with L-Valine and D-Lysine to form Z-L-norvaline. This compound has been shown to be insoluble in water and can be purified by chromatography. It also has an optical purity of 99%. The yield was found to be 100% for this reaction. Z-L-norvaline is an analogue of cyclosporin A because it shares many structural similarities as well as biological activities such as inhibition of prostaglandin synthesis and immunosuppression.

• Brand: Biosynth

Chemical properties

• Molecular weight: 251.28 g/mol
• Formula: C₁₃H₁₇NO₄
• Purity: Min. 95%