Neuromedin U, rat
CAS: 117505-80-3
Ref. 3D-FN73510
| 1mg | To inquire | |
| 2mg | To inquire | |
| 5mg | To inquire | |
| 250µg | To inquire | |
| 500µg | To inquire |
Product Information
- Nmu-23 (Rat)
- Nmu, Rat
- Ykvneyqgpvapsggfflfrprn-Nh2
- Tyr-Lys-Val-Asn-Glu-Tyr-Gln-Gly-Pro-Val-Ala-Pro-Ser-Gly-Gly-Phe-Phe-Leu-Phe-Arg-Pro-Arg-Asn-Nh2
- Neuromedin U
- H-Tyr-Lys-Val-Asn-Glu-Tyr-Gln-Gly-Pro-Val-Ala-Pro-Ser-
Neuromedin U is a peptide that has been found to have high binding affinity for 5-hydroxytryptamine (5-HT)2 receptors. Neuromedin U is also able to activate locomotor activity in rats, and has been shown to inhibit the growth of mammalian carcinoma cells in culture. This peptide binds to the 5-HT2 receptor and inhibits adenylyl cyclase activity, leading to a decrease in intracellular levels of cAMP and cytosolic Ca2+. The physiological effects of neuromedin U are mediated through its ability to stimulate pluripotent cells in the brain, as well as its ability to inhibit energy metabolism. Neuromedin U has also been shown to bind to polymerase chain reaction (PCR) primers, suggesting it may be used as a probe for DNA sequencing or gene mapping.
Chemical properties
Technical inquiry about: 3D-FN73510 Neuromedin U, rat
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