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Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
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Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

CAS: 330785-81-4

Ref. 3D-FNA78581

25g
193.00 €
50g
263.00 €
100g
372.00 €
250g
637.00 €
500g
937.00 €
Estimated delivery in United States, on Thursday 23 Jan 2025

Product Information

Name:
Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
Synonyms:
  • 4-(3-Chloro-4-Methoxy-Benzylamino) -2-Methylsulfanyl-Pyrimidine- 5-Carboxylic Acid Ethyl Ester
  • 4-(3-Chloro-4-methoxybenzylamino)-5-ethoxycarbonyl-2-methylthiopyrimidine
  • 4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecarboxylic acid ethyl ester
  • 5-Pyrimidinecarboxylic acid, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-, ethyl ester
  • Ethyl 4-(3-Chloro-4-Methoxybenzylamino)-2-(Methylthio)Pyrimidine-5-Carboxylate
  • Ethyl 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecarboxylate
Description:

Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate is an intermediate in the synthesis of avanafil. It is a precursor to the drug avanafil, which is used as a treatment for erectile dysfunction. This compound undergoes hydrolysis and condensation reactions to form a product with a reaction yield of 89%. The reaction proceeds sequentially by first forming an acetic acid ester, then adding ethyl bromoacetate, and finally hydrolyzing the ester.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
367.86 g/mol
Formula:
C16H18ClN3O3S
Purity:
Min. 95%
Color/Form:
Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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