13-Oxo-10-deacetyl Baccatin III

CAS: 92950-42-0

Ref. 3D-FO166622

Product Information

• Name: 13-Oxo-10-deacetyl Baccatin III
• Synonyms: 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-5,9(3H,6H)-dione, 12b-(acetyloxy)-12-(benzoyloxy)-2a,4,4a,10,11,12,12a,12b-octahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-, [2aR-(2aα,4β,4aβ,6β,11α,12α,12aα,12bα)]-, (2aR,4S,4aS,6R,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a,4,4a,10,11,12,12a,12b-octahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-5,9(3H,6H)-dione, 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-5,9(3H,6H)-dione, 12b-(acetyloxy)-12-(benzoyloxy)-2a,4,4a,10,11,12,12a,12b-octahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,11S,12S,12aR,12bS)-, 10-Deacetyl-13-oxobaccatin III

Description

13-Oxo-10-deacetyl Baccatin III is a diterpene that is found in the leaves of Taxus cuspidata. It has significant activity against taxanes, which are drugs used to treat cancer. This drug inhibits the growth of human colon adenocarcinoma cells, and medulloblastoma cells by affecting microtubules. 13-Oxo-10-deacetyl Baccatin III also has anti-inflammatory properties, and has been shown to inhibit prostaglandin synthesis in human liver cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 542.57 g/mol
• Formula: C₂₉H₃₄O₁₀
• Purity: Min. 95%
• Color/Form: Off-White Powder