Oxalic acid diimidazolide

CAS: 18637-83-7

Ref. 3D-FO49740

Product Information

• Name: Oxalic acid diimidazolide
• Synonyms: 1,1'-Oxalyldi-imidazole, 1H-Imidazole, 1,1'-(1,2-dioxo-1,2-ethanediyl)bis-, 1,2-di(1H-imidazol-1-yl)ethane-1,2-dione

Description

Oxalic acid diimidazolide is a fluorescence dye that has been used to detect the presence of cancerous cells in urine samples. It can be used as an alternative to acridine orange, which is more expensive and requires more safety precautions. Oxalic acid diimidazolide binds to RNA and DNA, which can be detected by flow cytometry or immunoassays. This compound was first synthesized in 1980 and its fluorescence properties were first described in 1984. The linear calibration curve for this compound was first reported in 1987. Fluorophores are attached to the nitrogen atoms in the molecule, which are then immobilized on a solid support by covalent bonding or adsorption. Immobilization of the fluorophore prevents it from diffusing away from its position on the support, allowing for easier detection of fluorescence emission.

• Brand: Biosynth

Chemical properties

• Molecular weight: 190.16 g/mol
• Formula: C₈H₆N₄O₂
• Purity: Min. 95%
• InChI: InChI=1S/C8H6N4O2/c13-7(11-3-1-9-5-11)8(14)12-4-2-10-6-12/h1-6H
• InChI key: InChIKey=ONRNRVLJHFFBJG-UHFFFAOYSA-N
• SMILES: O=C(C(=O)n1ccnc1)n1ccnc1