6-Oxo-1,6-Dihydro-Pyrimidine-5-Carboxylic Acid Ethyl Ester

CAS: 4786-52-1

Ref. 3D-FO57379

Product Information

• Name: 6-Oxo-1,6-Dihydro-Pyrimidine-5-Carboxylic Acid Ethyl Ester
• Synonyms: 4-Hydroxy-pyrimidine-5-carboxylic acid ethyl ester, 4-Hydroxypyrimidine-5-carboxylic acid ethyl ester, 5-Ethoxycarbonyl-4-hydroxypyrimidine, 5-Pyrimidinecarboxylic acid, 1,4-dihydro-4-oxo-, ethyl ester, 5-Pyrimidinecarboxylic acid, 1,6-dihydro-6-oxo-, ethyl ester, 5-Pyrimidinecarboxylic acid, 4-hydroxy-, ethyl ester, Ethyl 1,6-dihydro-6-oxo-5-pyrimidinecarboxylate, Ethyl 3,4-dihydro-4-oxopyrimidine-5-carboxylate, Ethyl 4-hydroxy-5-pyrimidinecarboxylate, NSC 69216

Description

6-Oxo-1,6-dihydro-pyrimidine-5-carboxylic acid ethyl ester is a potent inhibitor of the enzyme acetylcholinesterase. It binds to the active site of this enzyme and inhibits its activity by forming hydrogen bonds with key amino acid residues. 6-Oxo-1,6-dihydro-pyrimidine-5-carboxylic acid ethyl ester has a tautomeric equilibrium that is dependent on pH and temperature. The crystal structure of 6-oxo pyrimidine 5 carboxylic acid ethyl ester shows that it has a planar molecular geometry. This drug also has potential as a target molecule for future drug design in the treatment of Alzheimer's disease.

• Brand: Biosynth

Chemical properties

• Molecular weight: 168.15 g/mol
• Formula: C₇H₈N₂O₃
• Purity: Min. 95%
• InChI: InChI=1S/C7H8N2O3/c1-2-12-7(11)5-3-8-4-9-6(5)10/h3-4H,2H2,1H3,(H,8,9,10)
• InChI key: InChIKey=PLMIZYMXBHSARX-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1cnc[nH]c1=O