6-n-Propoxypurine

CAS: 5417-86-7

Ref. 3D-FP08052

Product Information

• Name: 6-n-Propoxypurine
• Synonyms: 1H-Purine, 6-propoxy-, 6-Propoxy-1H-purine, 6-Propoxy-9H-purine, 6-Propoxypurine, 6-propoxy-5H-purine, 6-propoxy-7H-purine, 9H-Purine, 6-propoxy-, NSC 11594, Purine, 6-propoxy-

Description

6-n-Propoxypurine (6-PP) is an intermediate in the purine biosynthetic pathway. It is a methylated adenosine analog that inhibits protein synthesis by inhibiting the enzyme ribonucleotide reductase and blocking the conversion of ribonucleotides to nucleotides. 6-PP also has autophagic activity, which may be due to its ability to decrease ATP levels. 6-PP is found in both cellular and extracellular environments, where it is converted into 6-dimethylaminopurine (6-DAP), a cytokinin with erythropoietic effects. 6-DAP can be methylated to produce 6-mercaptopurine riboside, a drug used for the treatment of some forms of cancer.

• Brand: Biosynth

Chemical properties

• Molecular weight: 178.19 g/mol
• Formula: C₈H₁₀N₄O
• Purity: Min. 95%
• InChI: InChI=1S/C8H10N4O/c1-2-3-13-8-6-7(10-4-9-6)11-5-12-8/h4-5H,2-3H2,1H3,(H,9,10,11,12)
• InChI key: InChIKey=UQQKEKTYLCCYSN-UHFFFAOYSA-N
• SMILES: CCCOc1ncnc2nc[nH]c12