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5-[4-Phenyl-5-(Trifluoromethyl)-2-Thienyl]-3-[3-(Trifluoromethyl)Phenyl]-1,2,4-Oxadiazole
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5-[4-Phenyl-5-(Trifluoromethyl)-2-Thienyl]-3-[3-(Trifluoromethyl)Phenyl]-1,2,4-Oxadiazole

CAS: 256414-75-2

Ref. 3D-FP101657

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Estimated delivery in United States, on Thursday 27 Jun 2024

Product Information

Name:
5-[4-Phenyl-5-(Trifluoromethyl)-2-Thienyl]-3-[3-(Trifluoromethyl)Phenyl]-1,2,4-Oxadiazole
Synonyms:
  • 1,2,4-Oxadiazole, 5-[4-phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]-
  • 5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole
  • 5-[4-Phenyl-5-(Trifluoromethyl)Thien-2-Yl]-3-[3-(Trifluoromethyl)Phenyl]-1,2,4-Oxadiazole
Description:

5-[4-Phenyl-5-(Trifluoromethyl)-2-Thienyl]-3-[3-(Trifluoromethyl)Phenyl]-1,2,4-Oxadiazole (5CZD) is a novel synthetic small molecule that acts as a potent and selective inhibitor of the enzyme methyltransferase. 5CZD has been shown to inhibit the activation of the p42/p44 mitogen activated protein kinases (MAPKs) in pancreatic cancer cells. This inhibition was mediated through a Sew2871 dependent mechanism and was associated with an increase in pluripotent stem cells in vitro. 5CZD also inhibited the proliferation of human embryonic stem cells, but not mouse embryonic stem cells, which may be due to its agonistic activity against mouse MAPKs.

Brand:
Biosynth
Long term storage:
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Chemical properties

Molecular weight:
440.36 g/mol
Formula:
C20H10F6N2OS
Purity:
Min. 95%
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Hazard Info

UN Number:
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Forbidden to fly:
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