Z-Pro-Met-OH

CAS: 17730-18-6

Ref. 3D-FP111513

Product Information

• Name: Z-Pro-Met-OH
• Synonyms: 1-[(Benzyloxy)Carbonyl]Prolylmethionine, 1-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</smallcap>-prolyl-<smallcap>L</span>-methionine, <span class="text-smallcaps">L</smallcap>-Methionine, 1-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-prolyl-, <span class="text-smallcaps">L</smallcap>-Methionine, N-[1-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-prolyl]-, Methionine, N-(1-carboxy-<span class="text-smallcaps">L</smallcap>-prolyl)-, N-benzyl ester, <smallcap>L</span>-, N-(1-((Phenylmethoxy)carbonyl)-L-prolyl)-L-methionine, NSC 334030
• CAS: 17730-18-6

Description

Z-Pro-Met-OH is a potent inhibitor of protein kinases. It has been shown to be resistant to peptidyl and sulphonium activation and also inhibits trypsin and other proteases. Z-Pro-Met-OH is a chloromethane derivative that is both an inhibitor of protein kinases and a substrate for the enzyme, which generates a constant concentration of product in the presence of enzyme. Z-Pro-Met-OH is more sensitive than other inhibitors tested to date, with the exception of staurosporine. It has sequence similarity to mammalian proteins, but lacks homology with any known protein.

Z-Pro-Met-OH inhibits the activity of several protein kinases, including tyrosine, serine/threonine, and dual specificity protein kinases. It has been shown to inhibit the activity of human tyrosine (tyrosine hydroxylase), human serine/threonine (phosphat

• Brand: Biosynth

Chemical properties

• Molecular weight: 380.46 g/mol
• Formula: C₁₈H₂₄N₂O₅S
• Purity: Min. 95%