4-(Piperidin-1-ylsulfonyl)aniline

CAS: 6336-68-1

Ref. 3D-FP112091

Product Information

• Name: 4-(Piperidin-1-ylsulfonyl)aniline
• Synonyms: 4-(Piperidin-1-Ylsulfonyl)Aniline

Description

4-(Piperidin-1-ylsulfonyl)aniline (4PSA) is a multidrug that inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 4PSA also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture. 4PSA has been shown to have anticancer activity against human lung cancer cells in vitro and in vivo. In addition, 4PSA has been found to inhibit

• Brand: Biosynth

Chemical properties

• Molecular weight: 240.32 g/mol
• Formula: C₁₁H₁₆N₂O₂S
• Purity: Min. 95%
• InChI: InChI=1S/C11H16N2O2S/c12-10-4-6-11(7-5-10)16(14,15)13-8-2-1-3-9-13/h4-7H,1-3,8-9,12H2
• InChI key: InChIKey=ZTTBIWZAAMPNBE-UHFFFAOYSA-N
• SMILES: Nc1ccc(S(=O)(=O)N2CCCCC2)cc1