6-Phenylpyridazin-3(2H)-one

CAS: 2166-31-6

Ref. 3D-FP124818

Product Information

• Name: 6-Phenylpyridazin-3(2H)-one
• Synonyms: 3(2H)-pyridazinone, 6-phenyl-3-phenyl-1H-pyridazin-6-one, 3(2H)-Pyridazinone, 6-phenyl-, 3-Phenyl-1H-pyridazin-6-one, 3-Phenyl-6-pyridazinone, 3-Phenyl-6-pyridazone, 3-Pyridazinol, 6-phenyl-, 6-Phenyl-2H-pyridazin-3-one, 6-Phenyl-3-pyridazinone, 6-Phenyl-3-pyridazone, 6-Phenylpyridazin-3-ol, NSC 13399

Description

6-Phenylpyridazin-3(2H)-one is a compound that has been shown to have thermodynamic and inhibitory effects on the hydrochloric acid reaction. This compound is also used for the treatment of autoimmune diseases, including rheumatoid arthritis and psoriasis, by inhibiting the production of inflammatory cytokines. 6-Phenylpyridazin-3(2H)-one inhibits Cox-2 through hydrogen bonding interactions with a cox-2 inhibitory site on the enzyme. The inhibition of this enzyme leads to decreased production of prostaglandins, which are involved in inflammation. 6-Phenylpyridazin-3(2H)-one also has been shown to be an inhibitor of platelet aggregation and may have antiplatelet effects.

• Brand: Biosynth

Chemical properties

• Molecular weight: 172.18 g/mol
• Formula: C₁₀H₈N₂O
• Purity: Min. 95%
• InChI: InChI=1S/C10H8N2O/c13-10-7-6-9(11-12-10)8-4-2-1-3-5-8/h1-7H,(H,12,13)
• InChI key: InChIKey=IJUIPRDMWWBTTQ-UHFFFAOYSA-N
• SMILES: O=c1ccc(-c2ccccc2)n[nH]1