2-[5-(Phenylcarbonyl)-2-thienyl]propanoic acid

CAS: 33005-95-7

Ref. 3D-FP137544

Product Information

• Name: 2-[5-(Phenylcarbonyl)-2-thienyl]propanoic acid
• Synonyms: (RS)-Tiaprofenic acid, 2-(5-Benzoylthiophen-2-Yl)Propanoic Acid, 2-(5-Benzoylthiophen-2-yl)propanoicacid, 2-Thiopheneacetic acid, 5-benzoyl-α-methyl-, 5-Benzoyl-α-methyl-2-thiopheneacetic acid, Acide Tiaprofenique, Acido Tiaprofenico, Fc 3001, Ru 15060, Suralgan, Surgam, Tiaprofen, Tiaprofenic acid, Tiaprofeninsaure, α-(5-Benzoyl-2-thienyl)propionic acid
• CAS: 33005-95-7

Description

2-[5-(Phenylcarbonyl)-2-thienyl]propanoic acid is a nonsteroidal anti-inflammatory drug that inhibits the production of prostaglandin E2 (PGE2) by inhibiting cyclooxygenase. It has been shown to inhibit tumor metastasis in animal models and to have an anti-inflammatory activity. 2-[5-(Phenylcarbonyl)-2-thienyl]propanoic acid has also shown anticancer activity in vitro and in vivo, as well as a synergistic interaction with chemotherapeutic drugs.

• Brand: Biosynth

Chemical properties

• Molecular weight: 260.31 g/mol
• Formula: C₁₄H₁₂O₃S
• Purity: Min. 95%
• InChI: InChI=1S/C14H12O3S/c1-9(14(16)17)11-7-8-12(18-11)13(15)10-5-3-2-4-6-10/h2-9H,1H3,(H,16,17)
• InChI key: InChIKey=GUHPRPJDBZHYCJ-UHFFFAOYSA-N
• SMILES: CC(C(=O)O)c1ccc(C(=O)c2ccccc2)s1