1-Phenylpiperidine-4-carboxylic acid

CAS: 94201-40-8

Ref. 3D-FP140862

Product Information

• Name: 1-Phenylpiperidine-4-carboxylic acid
• Synonyms: 4-Piperidinecarboxylic acid, 1-phenyl-, 1-Phenyl-4-piperidinecarboxylic acid

Description

1-Phenylpiperidine-4-carboxylic acid is a non-steroidal agent that has been shown to reduce blood glucose in animal models. It also reduces postprandial glucose levels and improves insulin sensitivity. This compound binds to the glucagon-like peptide 1 receptor (GLP-1R) and inhibits glucagon secretion, leading to an increase in insulin release. 1-Phenylpiperidine-4-carboxylic acid has a high lipophilicity and is metabolised by CYP3A4. It can be used as a starting point for optimization of oral glucose lowering drugs with greater potential for activity and less toxicity than existing treatments.

• Brand: Biosynth

Chemical properties

• Molecular weight: 205.25 g/mol
• Formula: C₁₂H₁₅NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C12H15NO2/c14-12(15)10-6-8-13(9-7-10)11-4-2-1-3-5-11/h1-5,10H,6-9H2,(H,14,15)
• InChI key: InChIKey=IXLCEJNZWAYHPL-UHFFFAOYSA-N
• SMILES: O=C(O)C1CCN(c2ccccc2)CC1