5-Phenylthiazol-2-amine

CAS: 39136-63-5

Ref. 3D-FP144391

Product Information

• Name: 5-Phenylthiazol-2-amine
• Synonyms: 2-Amino-5-phenyl-1,3-thiazole, 2-Amino-5-phenylthiazol, 2-Amino-5-phenylthiazole, 2-Thiazolamine, 5-phenyl-, 5-Phenyl-1,3-Thiazol-2-Amine, 5-Phenyl-2-aminothiazole, 5-Phenyl-2-thiazolamine, 5-Phenyl-Thiazol-2-Ylamine, Thiazole, 2-amino-5-phenyl-
• CAS: 39136-63-5

Description

5-Phenylthiazol-2-amine is a chemical compound with clinical use in the synthesis of dyestuffs and as an intermediate for pharmaceuticals. It is also used for the treatment of cancer, although its clinical efficacy has not been proven. The cellular process that 5-phenylthiazol-2-amine inhibits is the shikimate pathway, which is involved in bacterial metabolism. This compound also inhibits kinases and may be used to treat cancer. 5-Phenylthiazol-2-amine can be synthesized from 2-(4'-nitrophenoxy)benzaldehyde or 2-(4'-nitrophenoxy)benzaldehyde chloride. This chemical reacts with ammonia or ammonium chloride to produce 5-(phenylamino)-1,3,4-thiadiazole (5PT). The reaction mechanism involves nucleophilic substitution at the nitro group followed by hydrolysis of the nitro group to form a

• Brand: Biosynth

Chemical properties

• Molecular weight: 176.24 g/mol
• Formula: C₉H₈N₂S
• Purity: Min. 95%