N-Piperidin-4-yl-benzamide

CAS: 33953-37-6

Ref. 3D-FP147111

Product Information

• Name: N-Piperidin-4-yl-benzamide
• Synonyms: 4-(Phenylcarboxamido)piperidine, 4-(Piperidin-4-Yl)Benzamide, 4-Benzamidopiperidine, Benzamide, N-4-piperidinyl-, Benzamide, N-4-piperidyl-, N-(4-Piperidinyl)benzamide, N-(Piperidin-4-yl)benzamide, N-4-Piperidinylbenzamide
• CAS: 33953-37-6

Description

N-Piperidin-4-yl-benzamide is an orally active anticancer agent that inhibits the growth of tumor cells by inhibiting the phosphorylation of HIF-1α. It also has a potential to inhibit quaternary ammonium salt metabolism and antimalarial activity. N-Piperidin-4-yl-benzamide is metabolized in vitro, but there are no data on its pharmacokinetic properties. It has been evaluated in clinical trials for cancer treatment and has shown good tolerability and efficacy. N-piperidin-4-ylbenzamide may also be used to treat malaria, as it has been shown to have antimalarial activity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 204.27 g/mol
• Formula: C₁₂H₁₆N₂O
• Purity: Min. 95%
• InChI: InChI=1S/C12H16N2O/c15-12(10-4-2-1-3-5-10)14-11-6-8-13-9-7-11/h1-5,11,13H,6-9H2,(H,14,15)
• InChI key: InChIKey=JMQDNLCNCDSHNC-UHFFFAOYSA-N
• SMILES: O=C(NC1CCNCC1)c1ccccc1