2,3-Pyridinedicarboxylic acid dimethylester

CAS: 605-38-9

Ref. 3D-FP149112

Product Information

• Name: 2,3-Pyridinedicarboxylic acid dimethylester
• Synonyms: 2,3-Bis(methoxycarbonyl)pyridine, 2,3-Dimethyl 2,3-pyridinedicarboxylate, 2,3-Dimethyl pyridine-2,3-dicarboxylate, 2,3-Pyridinedicarboxylic acid dimethyl ester, 2,3-Pyridinedicarboxylic acid, 2,3-dimethyl ester, Dimethyl 2,3-pyridinedicarboxylate, Dimethyl Pyridine-2,3-Dicarboxylate, Dimethyl quinolinate, NSC 17026, Quinolinic acid dimethyl ester
• CAS: 605-38-9

Description

2,3-Pyridinedicarboxylic acid dimethylester (PDDE) is a methylated derivative of 3-nitrophthalic anhydride. It has been shown to be a stereoselective receptor blocker that binds to the glutamate site of the N-methyl-D-aspartate receptor. PDDE has also been shown to have high affinity for the cerebral cortex and is able to penetrate the blood brain barrier. PDDE blocks the NMDA receptor by binding to it and preventing ion flow, which leads to inhibition of neurotransmitter release. This drug is used as an injectable methyl derivative with a molecule weight of 217. The ionization detector can detect PDDE in tetrahydrofuran at concentrations of 1,000 ng/mL or less.

• Brand: Biosynth

Chemical properties

• Molecular weight: 195.17 g/mol
• Formula: C₉H₉NO₄
• Purity: Min. 95%