4-[(Pyridine-3-carbonyl)amino]butyric acid

CAS: 34562-97-5

Ref. 3D-FP15522

Product Information

• Name: 4-[(Pyridine-3-carbonyl)amino]butyric acid
• Synonyms: Pikamilone, 4-((Pyridine-3-Carbonyl)-Amino)-Butyric Acid, 4-(Nicotinamido)butanoic acid, 4-Nicotinoylamino-Butyric Acid, 4-[(3-Pyridinylcarbonyl)amino]butanoic acid, 4-[(Pyridin-3-Ylcarbonyl)Amino]Butanoic Acid, Butanoic acid, 4-[(3-pyridinylcarbonyl)amino]-, Butyric acid, 4-nicotinamido-, N-Nicotinoyl-γ-aminobutyric acid, Nicotinoyl-GABA, Nicotinoyl-γ-aminobutyric acid, Picamilon, Sodium 4-[(Pyridin-3-Ylcarbonyl)Amino]Butanoate
• CAS: 34562-97-5

Description

4-[(Pyridine-3-carbonyl)amino]butyric acid (4-PBA) is a non-proteinogenic amino acid that has been found in food and has been shown to have therapeutic effects on a number of diseases. 4-PBA is converted to gamma-aminobutyric acid (GABA) by the enzyme GABA transaminase. It also has a synergistic effect with sodium succinate, which is another precursor in the production of GABA. This synergistic effect increases the amount of GABA produced from 4-PBA and sodium succinate when they are consumed together. 4-PBA also binds to receptors for dopamine, which may be why it is effective for treating diabetic neuropathy and Parkinson's disease.

• Brand: Biosynth

Chemical properties

• Molecular weight: 208.21 g/mol
• Formula: C₁₀H₁₂N₂O₃
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C10H12N2O3/c13-9(14)4-2-6-12-10(15)8-3-1-5-11-7-8/h1,3,5,7H,2,4,6H2,(H,12,15)(H,13,14)
• InChI key: InChIKey=NAJVRARAUNYNDX-UHFFFAOYSA-N
• SMILES: O=C(O)CCCNC(=O)c1cccnc1