3-(2-Pyridinylamino)-propanol

CAS: 19068-80-5

Ref. 3D-FP165615

Product Information

• Name: 3-(2-Pyridinylamino)-propanol
• Synonyms: 1-Propanol, 3-(2-Pyridinylamino)-, 3-(Pyridin-2-ylamino)propan-1-ol

Description

3-(2-Pyridinylamino)-propanol is a potent inhibitor of integrin αIIbβ3, which is an important receptor for platelet aggregation. 3-(2-Pyridinylamino)-propanol also inhibits the binding of fibrinogen to the receptor and the activation of phospholipase A2 in human neutrophils. The basic moieties of 3-(2-pyridinylamino)-propanol are thought to be responsible for its potency and selectivity for integrin αIIbβ3. This drug can be used as a research tool to study platelet aggregation and has potential as a therapeutic agent for thrombotic disorders such as coronary artery disease or stroke.

• Brand: Biosynth

Chemical properties

• Molecular weight: 152.19 g/mol
• Formula: C₈H₁₂N₂O
• Purity: Min. 95%
• InChI: InChI=1S/C8H12N2O/c11-7-3-6-10-8-4-1-2-5-9-8/h1-2,4-5,11H,3,6-7H2,(H,9,10)
• InChI key: InChIKey=QTTQBQLTBUGHCD-UHFFFAOYSA-N
• SMILES: OCCCNc1ccccn1