4-Piperidinecarboxylic acid tert-butyl ester

CAS: 138007-24-6

Ref. 3D-FP167245

Product Information

• Name: 4-Piperidinecarboxylic acid tert-butyl ester
• Synonyms: Tert-Butyl Piperidine-4-Carboxylate

Description

4-Piperidinecarboxylic acid tert-butyl ester is a potent spindle poison that was designed to target the mitotic spindle. The compound has been shown to inhibit cell proliferation in cancer cells and prostate cancer cells, while also inhibiting the progression of metastatic castration-resistant prostate cancer. 4-Piperidinecarboxylic acid tert-butyl ester binds to the cytoskeleton and blocks polymerization of tubulin into microtubules. This binding prevents the formation of a mitotic spindle, which is required for cell division.

• Brand: Biosynth

Chemical properties

• Molecular weight: 185.26 g/mol
• Formula: C₁₀H₁₉NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C10H19NO2/c1-10(2,3)13-9(12)8-4-6-11-7-5-8/h8,11H,4-7H2,1-3H3
• InChI key: InChIKey=FUYBPBOHNIHCHM-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)C1CCNCC1