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Pregnenolone-16α-carbonitrile
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Pregnenolone-16α-carbonitrile

CAS: 1434-54-4

Ref. 3D-FP168503

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Estimated delivery in United States, on Thursday 23 Jan 2025

Product Information

Name:
Pregnenolone-16α-carbonitrile
Controlled Product
Synonyms:
  • Pregnenolone Carbonitrile
  • (3Beta,16Alpha)-3-Hydroxy-20-Oxopregn-5-Ene-16-Carbonitrile
  • (3β,16α)-3-Hydroxy-20-oxopregn-5-ene-16-carbonitrile
  • 16α-Cyanopregnenolone
  • 3beta-Hydroxy-20-oxo-5-pregnene-16alpha-carbonitrile
  • 3β-Hydroxy-20-oxo-5-pregnen-16α-carbonitrile
  • 3β-Hydroxy-20-oxopregn-5-ene-16α-carbonitrile
  • Ccris 9224
  • Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3beta,16alpha)-
  • Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3β,16α)-
  • See more synonyms
  • Pregn-5-ene-16α-carbonitrile, 3β-hydroxy-20-oxo-
  • Pregn-5-ene-3β-ol-20-oxo-16α-carbonitrile
  • Pregnenolone 16alpha-carbonitrile
  • Pregnenolone 16α-carbonitrile
  • Pregnenolone carbonitrile
  • Sc 4674
  • PCN
Description:

Pregnenolone-16alpha-carbonitrile is a synthetic pregnane steroid that is a metabolite of progesterone. It has been shown to be active against liver cells, and has been used as an inhibitor for detoxification enzymes. The reaction mechanism of pregnenolone-16alpha-carbonitrile can be described as follows: the carbonitrile group binds to the active site of cytochrome P450, while the 16α-hydroxyl group binds to the heme moiety in the enzyme. This binding inhibits p450 activity, leading to changes in enzyme activities and energy metabolism. Pregnenolone-16alpha-carbonitrile also has a strong affinity for DNA binding domains, which may lead to transcriptional regulation.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
341.49 g/mol
Formula:
C22H31NO2
Purity:
Min. 95%
MDL:
Melting point:
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Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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