1,4-Phenylene-bis-maleimide

CAS: 3278-31-7

Ref. 3D-FP26949

Product Information

• Name: 1,4-Phenylene-bis-maleimide
• Synonyms: 1,4-PDMp-N,N'-Phenylenebismaleimidep-Phenylene dimaleimide, 1,1'-benzene-1,4-diylbis(1H-pyrrole-2,5-dione), 1,1′-(1,4-Phenylene)bis[1H-pyrrole-2,5-dione], 1,4-Bismaleimidobenzene, 1,4-Dimaleimidobenzene, 1,4-Phenylenebismaleimide, 1-[4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl]-2,5-dihydro-1H-pyrrole-2,5-dione, 1-[4-(2,5-Dioxopyrrol-1-yl)phenyl]pyrrole-2,5-dione, 1H-Pyrrole-2,5-dione, 1,1′-(1,4-phenylene)bis-, 4,4′-Phenylenedimaleimide, Maleimide, N,N′-p-phenylenedi-, N,N'-1,4-Phenylenedimaleimide, N,N′-1,4-Phenylenebismaleimide, N,N′-p-Phenylenebis(maleimide), NSC 81257, p-N,N′-Phenylenebismaleimide, p-Phenylene dimaleimide

Description

1,4-Phenylene-bis-maleimide is a chemical crosslinking agent that has been used to study the function of actin subunits. It binds to the amino acid composition of actin monomers, and then forms a covalent bond with the cysteine residue in the actin protein. This binding can be reversed by reducing agents such as dithiothreitol or glutathione. The fluorescence properties of 1,4-phenylene bis-maleimide depend on its reactivity with actin filaments. The fluorescence resonance experiments show that this chemical can reversibly bind to actin subunits. This agent is reactive and can form crosslinks with other proteins.

• Brand: Biosynth

Chemical properties

• Molecular weight: 268.22 g/mol
• Formula: C₁₄H₈N₂O₄
• Purity: Min. 95%
• InChI: InChI=1S/C14H8N2O4/c17-11-5-6-12(18)15(11)9-1-2-10(4-3-9)16-13(19)7-8-14(16)20/h1-8H
• InChI key: InChIKey=AQGZJQNZNONGKY-UHFFFAOYSA-N
• SMILES: O=C1C=CC(=O)N1c1ccc(N2C(=O)C=CC2=O)cc1