(R)-2-Pyrrolidinone-5-carboxylic acid

CAS: 4042-36-8

Ref. 3D-FP27357

Product Information

• Name: (R)-2-Pyrrolidinone-5-carboxylic acid
• Synonyms: D-Pyroglutamic acidD-Pyrrolidinonecarboxylic acidD-Pyrrolidonecarboxylic acid, (+)-2-Pyrrolidone-5-carboxylic acid, (+)-<span class="text-smallcaps">D</span>-Pyroglutamic acid, (+)-Pyroglutamic acid, (2R)-2-Carboxy-5-pyrrolidinone, (2R)-5-Oxopyrrolidine-2-carboxylic acid, (R)-(+)-2-Pyrrolidinone-5-carboxylic acid, (R)-(+)-2-Pyrrolidone-5-carboxylic acid, (R)-(+)-5-Oxopyrrolidine-2-carboxylic acid, (R)-5-Oxoproline, (R)-Pyroglutamic acid, 2-Oxopyrrolidine-1-Carboxylic Acid, 5-Oxo-<span class="text-smallcaps">D</span>-proline, <span class="text-smallcaps">D</span>-2-Pyrrolidone-5-carboxylic acid, <span class="text-smallcaps">D</span>-Pidolic acid, <span class="text-smallcaps">D</span>-Proline, 5-oxo-, <span class="text-smallcaps">D</span>-Pyrrolidinonecarboxylic acid, <span class="text-smallcaps">D</span>-Pyrrolidonecarboxylic acid, D-5-Pyrrolidone-2-carboxylic acid, D-Pyroglutamic acid, H-D-Pyr-OH, Proline, 5-oxo-, <span class="text-smallcaps">D</span>-, D-Proline, 5-oxo-, D-2-Pyrrolidone-5-carboxylic acid, 5-Oxo-D-proline, D-Pyrrolidonecarboxylic acid, Proline, 5-oxo-, D-

Description

(R)-2-Pyrrolidinone-5-carboxylic acid is an endogenous metabolite of glutamate. It has been shown to be present in mammalian tissues and urine samples. The uptake of (R)-2-pyrrolidinone-5-carboxylic acid into rat kidney cells and its conversion to glutamine was observed following treatment with gamma aminobutyric acid, a neurotransmitter that regulates the activity of the kidney tubule cells. The presence of this metabolite may provide evidence for a potential role in the progression of atherosclerotic cardiovascular disease. This compound may also play a role in regulating cation channel activity, which could be useful for developing new drugs for treating epilepsy and other neurological disorders.

• Brand: Biosynth

Chemical properties

• Molecular weight: 129.11 g/mol
• Formula: C₅H₇NO₃
• Purity: Min. 95%
• InChI: InChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m1/s1
• InChI key: InChIKey=ODHCTXKNWHHXJC-GSVOUGTGSA-N
• SMILES: O=C1CC[C@H](C(=O)O)N1