L-Pyroglutamyl-L-histidyl-L-prolinamide

CAS: 24305-27-9

Ref. 3D-FP33965

Product Information

• Name: L-Pyroglutamyl-L-histidyl-L-prolinamide
• Synonyms: ProtirelinThyrotropin-Releasing Hormone, (Pyro)-<span class="text-smallcaps">L</smallcap>-glutamic acid-<smallcap>L</smallcap>-histidine-<smallcap>L</span>-proline-NH₂, (Pyro)-L-glutamic acid-L-histidine-L-proline-NH2, 252: PN: WO2010033207 SEQID: 378 claimed protein, 5-Oxo-<span class="text-smallcaps">L</smallcap>-prolyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-prolinamide, 83: PN: US20090175821 PAGE: 403 claimed protein, <span class="text-smallcaps">L</smallcap>-Prolinamide, 5-oxo-<smallcap>L</smallcap>-prolyl-<smallcap>L</span>-histidyl-, <span class="text-smallcaps">L</smallcap>-Pyroglutamyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-prolinamide, <span class="text-smallcaps">L</smallcap>-Pyroglutamyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-proline amide, Abbott 38579, Antepan, Fda 1725, L-Pyroglutamyl-L-histidyl-L-proline amide, Lopremone, Prem, Protirelin, Protirelina, Protireline, Relefact TRH, Rifathyroin, Rifotironin, Ro 8-6270/9, Stimu TSH, Synthetic TRF, Synthetic TRH, Synthetic TSH-releasing factor, Synthetic TSH-releasing hormone, Synthetic thyrotropin-releasing factor, Synthetic thyrotropin-releasing hormone, TRF, TRH, TSH-releasing factor, TSH-releasing hormone, Thypinone, Thyrefact, Thyroid releasing hormone, Thyroid-stimulating hormone-releasing factor, Thyroliberin, Thyrotropic hormone-releasing factor, Thyrotropic hormone-releasing hormone, Thyrotropic releasing hormone, Thyrotropic-releasing factor, Thyrotropin-releasing factor, Thyrotropin-releasing hormone, Tsh-Rf
• CAS: 24305-27-9

Description

L-Pyroglutamyl-L-histidyl-L-prolinamide (PGC) is a pyrrolidine that is used for the treatment of neurologic disorders. It has been shown to be effective in treating depression and a number of other neurologic disorders, including Parkinson's disease, Alzheimer's disease, and epilepsy. PGC has also been shown to have an antidepressant effect in women with depression who are pregnant or have recently given birth. In addition, it has been found to be clinically effective in the treatment of symptoms associated with Parkinson’s Disease. PGC is not absorbed into the bloodstream and must be injected directly into muscle tissue or fat cells in order to produce its therapeutic effects.

• Brand: Biosynth

Chemical properties

• Molecular weight: 362.38 g/mol
• Formula: C₁₆H₂₂N₆O₄
• Purity: Min. 95%
• Color/Form: White Powder