Z-DL-Phe-OH

CAS: 3588-57-6

Ref. 3D-FP39013

Product Information

• Name: Z-DL-Phe-OH
• Synonyms: 2-((Benzyloxycarbonyl)amino)-3-phenylpropanoic acid, 3-Phenyl-2-(phenylmethoxycarbonylamino)propanoic acid, <span class="text-smallcaps">DL</span>-(Carbobenzyloxy)phenylalanine, <span class="text-smallcaps">DL</span>-Cbz phenylalanine, <span class="text-smallcaps">DL</span>-N-(Benzoxycarbonyl)phenylalanine, Alanine, N-carboxy-3-phenyl-, N-benzyl ester, <span class="text-smallcaps">DL</span>-, Carbobenzoxy-<span class="text-smallcaps">DL</span>-phenylalanine, Carbobenzoxyphenylalanine, Cbz-DL-phenylalanine, N-(Benzyloxycarbonyl)-<span class="text-smallcaps">DL</span>-phenylalanine, N-(Benzyloxycarbonyl)-dl-phenylalanine, N-(Carbobenzyloxy)-<span class="text-smallcaps">D</smallcap><smallcap>L</span>-phenylalanine, N-Carbenzoxy-DL-phenylalanine, N-Carbobenzoxy-<span class="text-smallcaps">DL</span>-phenylalanine, N-Carbobenzoxy-DL-phenylalanine, N-[(Phenylmethoxy)carbonyl]phenylalanine, N-benzyloxycarbonyl-DL-3-phenylalanine, NSC 333486, Phenylalanine, N-[(phenylmethoxy)carbonyl]-, Carbobenzoxy-DL-phenylalanine, Alanine, N-carboxy-3-phenyl-, N-benzyl ester, DL-

Description

Z-DL-Phe-OH is a potent and selective inhibitor of serine protease. It is an irreversible inhibitor that binds to the active site of the enzyme and blocks the formation of the substrate-enzyme complex, inhibiting protein synthesis. Z-DL-Phe-OH has been shown to inhibit trypsin, chymotrypsin, carboxypeptidase A, papain and elastase. This compound also inhibits aminopeptidases such as leucine aminopeptidase (LAP) and aminopeptidase N (APN). In addition, it inhibits dipeptidyl peptidases IV (DP IV), which are enzymes that break down amino acid chains into individual amino acids. The inhibition of DP IV results in increased levels of dipeptides in blood plasma. Z-DL-Phe-OH has been shown to be selective for serine proteases over other types of

• Brand: Biosynth

Chemical properties

• Molecular weight: 299.32 g/mol
• Formula: C₁₇H₁₇NO₄
• Purity: Min. 95%
• InChI: InChI=1S/C17H17NO4/c19-16(20)15(11-13-7-3-1-4-8-13)18-17(21)22-12-14-9-5-2-6-10-14/h1-10,15H,11-12H2,(H,18,21)(H,19,20)
• InChI key: InChIKey=RRONHWAVOYADJL-UHFFFAOYSA-N
• SMILES: O=C(NC(Cc1ccccc1)C(=O)O)OCc1ccccc1