Z-L-proline 4-nitrophenyl ester

CAS: 3304-59-4

Ref. 3D-FP47307

Product Information

• Name: Z-L-proline 4-nitrophenyl ester
• Synonyms: Z-L-Pro-ONp(S)-Z-pyrrolidine-2- carboxylic acid 4-nitrophenyl ester, 1,2-Pyrrolidinedicarboxylic acid, 1-benzyl p-nitrophenyl ester, <span class="text-smallcaps">L</span>-, 1,2-Pyrrolidinedicarboxylic acid, 2-(4-nitrophenyl) 1-(phenylmethyl) ester, (2S)-, 1,2-Pyrrolidinedicarboxylic acid, 2-(4-nitrophenyl) 1-(phenylmethyl) ester, (S)-, 1-Benzyl 2-(4-Nitrophenyl) Pyrrolidine-1,2-Dicarboxylate, 1-O-Benzyl 2-O-(4-nitrophenyl) (2S)-pyrrolidine-1,2-dicarboxylate, 1-benzyl 2-(4-nitrophenyl) (2S)-pyrrolidine-1,2-dicarboxylate, 2-(4-Nitrophenyl) 1-(phenylmethyl) (2S)-1,2-pyrrolidinedicarboxylate, N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-proline 4-nitrophenyl ester, N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-proline p-nitrophenyl ester, N-Carbobenzoxy-<span class="text-smallcaps">L</span>-proline p-nitrophenyl ester, N-Carbobenzoxy-S-proline-p-nitrophenylester, Z-Pro-ONp
• CAS: 3304-59-4

Description

Z-L-proline 4-nitrophenyl ester is a synthetic protease inhibitor that is active at acidic pH. It has been shown to be effective against the proteolytic activity of soybean trypsin and collagenase. Z-L-proline 4-nitrophenyl ester also stabilizes fibrinogen and inhibits the lysis of cells in culture, making it useful for cell culture work. This agent has been shown to inhibit the activity of a number of proteases including those from animals, bacteria, and yeast. The synthesis of this compound was based on the structure of the natural substrate, L-proline, which is found in proteins throughout nature. The sequence of this compound is related to that found in some natural protein inhibitors such as sephacryl and benzamidine.

• Brand: Biosynth

Chemical properties

• Molecular weight: 370.36 g/mol
• Formula: C₁₉H₁₈N₂O₆
• Purity: Min. 95%