Phe-Gly-OH

CAS: 721-90-4

Ref. 3D-FP48212

Product Information

• Name: Phe-Gly-OH
• Synonyms: L-Phenylalanylglycine, 105: PN: US20130123467 SEQID: 128 claimed protein, 2-[(2S)-2-Amino-3-phenylpropanamido]acetic acid, 2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]acetic acid, 28: PN: WO2016049036 SEQID: 69 claimed protein, <span class="text-smallcaps">L</span>-Phenylalanylglycine, Glycine, <span class="text-smallcaps">L</span>-phenylalanyl-, Glycine, N-(3-phenyl-<span class="text-smallcaps">L</span>-alanyl)-, Glycine, N-<span class="text-smallcaps">L</span>-phenylalanyl-, H-Phe-Gly-OH, NSC 89182, Phe-Gly hydrate, Phenylalanylglycine, {[(2S)-2-ammonio-3-phenylpropanoyl]amino}acetate

Description

Phe-Gly-OH is a cyclic peptide with a hydroxyl group on the phenyl ring. It has been used as a model system for studying the uptake of drugs by cells. Phe-Gly-OH is taken up by cells in the proximal tubules of the kidney, where it forms disulfide bonds with proteins and inhibits enzyme activities. In tissue culture, Phe-Gly-OH has shown cytotoxicity to cervical cancer cells. It also binds to thrombin receptors and prevents platelet aggregation, which may be due to its ability to inhibit adenine nucleotide synthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 222.24 g/mol
• Formula: C₁₁H₁₄N₂O₃
• Purity: Min. 95%
• InChI: InChI=1S/C11H14N2O3/c12-9(11(16)13-7-10(14)15)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,16)(H,14,15)/t9-/m0/s1
• InChI key: InChIKey=GLUBLISJVJFHQS-VIFPVBQESA-N
• SMILES: N[C@@H](Cc1ccccc1)C(=O)NCC(=O)O