2-Piperazin-1-yl-benzothiazole
CAS: 55745-83-0
Ref. 3D-FP50777
| 1g | To inquire | |
| 2g | To inquire | |
| 5g | To inquire | |
| 500mg | To inquire |
Product Information
- 2-(1-Piperazinyl)-1,3-benzothiazole2-Piperazino-1,3-benzothiazole
- 1-(Benzothiazol-2-yl)piperazine
- 2-(1-Piperazinyl)-1,3-benzothiazole
- Benzothiazole, 2-(1-piperazinyl)-
2-Piperazin-1-yl-benzothiazole is an agent that acts as a serotonin 5HT1a receptor agonist. The drug has been shown to be effective in the treatment of HIV infection. It was found that 2-piperazin-1-yl-benzothiazole inhibited transcriptional regulation by blocking the phosphorylation of the transcriptional regulator, CREB. This resulted in decreased expression of genes responsible for viral replication and increased expression of genes required for T cell activation. The drug is currently under investigation as a potential treatment for schizophrenia and Parkinson's disease.
2-Piperazin-1-yl-benzothiazole can also act as a silico probe. A study has shown that it binds to human dopamine D2 receptors and inhibits dopamine release from synaptosomes, leading to increased levels of dopamine in the brain. This may be due to its ability to bind to both dopamine D2 and serotonin
Chemical properties
Technical inquiry about: 3D-FP50777 2-Piperazin-1-yl-benzothiazole
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