4-(1H-Pyrazol-1-yl)benzoic acid

CAS: 16209-00-0

Ref. 3D-FP50781

Product Information

• Name: 4-(1H-Pyrazol-1-yl)benzoic acid
• Synonyms: 4-(1H-pyrazol-1-yl)benzoate

Description

4-(1H-Pyrazol-1-yl)benzoic acid (4H-PBA) is an upcoming, reversibly, potential risk, sustainable, catalytic, synthetic ligand. It has a high affinity for the enzyme formate dehydrogenase and can be used to produce formate as a potential energy source. 4H-PBA is synthesized from formic acid and ammonia in the presence of hydrazine. The reaction produces formate as a byproduct. This process was shown to have no significant effect on the volumetric or densities of formic acid or formate. 4H-PBA has also been shown to inhibit oxidative phosphorylation in rat liver mitochondria, which may lead to cell death by apoptosis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 188.18 g/mol
• Formula: C₁₀H₈N₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C10H8N2O2/c13-10(14)8-2-4-9(5-3-8)12-7-1-6-11-12/h1-7H,(H,13,14)
• InChI key: InChIKey=XOEKYPIBVOGCDG-UHFFFAOYSA-N
• SMILES: O=C(O)c1ccc(-n2cccn2)cc1