3-(Piperidin-1-ylmethyl)aniline

CAS: 93138-55-7

Ref. 3D-FP50953

Product Information

• Name: 3-(Piperidin-1-ylmethyl)aniline
• Synonyms: [3-(Piperidin-1-ylmethyl)phenyl]amine, 3-Piperidin-1-ylmethyl-phenylamine, Benzenamine, 3-(1-piperidinylmethyl)-, 3-(1-Piperidinylmethyl)aniline

Description

3-(Piperidin-1-ylmethyl)aniline is an inhibitor of the muscle-type voltage-gated potassium channel. It is expressed in skeletal muscle and modulates the activity of these channels. 3-(Piperidin-1-ylmethyl)aniline has been shown to inhibit cell toxicity caused by azobenzene and ionizing radiation, as well as to inhibit the activity of a variety of ion channels. The selectivity of 3-(piperidin-1-ylmethyl)aniline for potassium channels is based on its ability to bind to a specific site on the channel protein that is distinct from other known blockers. Electrophysiological studies have demonstrated that 3-(piperidin-1-ylmethyl)aniline blocks currents through potassium channels with high affinity and modulates their activity in a reversible manner.

• Brand: Biosynth

Chemical properties

• Molecular weight: 190.28 g/mol
• Formula: C₁₂H₁₈N₂
• Purity: Min. 95%
• InChI: InChI=1S/C12H18N2/c13-12-6-4-5-11(9-12)10-14-7-2-1-3-8-14/h4-6,9H,1-3,7-8,10,13H2
• InChI key: InChIKey=SEJNYLBEEMVJNN-UHFFFAOYSA-N
• SMILES: Nc1cccc(CN2CCCCC2)c1