1H-Pyrazolo[3,4-c]pyridine
CAS: 271-47-6
Ref. 3D-FP51890
1g | To inquire | ||
2g | To inquire | ||
5g | To inquire | ||
10g | To inquire | ||
500mg | To inquire |
Product Information
1H-Pyrazolo[3,4-c]pyridine is a potent inhibitor of the ATP binding site in the ATP synthase. It has been shown to inhibit cellular proliferation and induce apoptosis in cancer cells. 1H-Pyrazolo[3,4-c]pyridine binds to and inhibits the activity of Pim-1 kinase. This compound has been shown to be effective against two isoforms of Pim-1 kinase: pim-1A and pim-1B. Substitution of groups on the piperidine ring or at position 3 leads to increased potency against both isoforms, but with different affinities. Evaluation of this compound's effect on tumor growth is ongoing.
Chemical properties
Technical inquiry about: 3D-FP51890 1H-Pyrazolo[3,4-c]pyridine
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