PBD-5,11-dione
CAS: 138865-23-3
Ref. 3D-FP52573
| 1g | Discontinued | ||
| 2g | Discontinued | ||
| 5g | Discontinued | ||
| 500mg | Discontinued |
Product Information
Name:
PBD-5,11-dione
Synonyms:
- (S)-1,2,3,11a-Tetrahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11-dione
- 1H-Pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H,11aH)-dione, 2,3-dihydro-, dihydrate,(S)- (9CI)
Description:
PBD-5,11-dione is a natural compound that has been shown to have anti-cancer properties. PBD-5,11-dione inhibits the growth of cervical cancer cells by inducing apoptosis. In addition, this compound blocks the production of prostaglandin J2 (PGJ2) and reduces the mitochondrial membrane potential (ΔΨm). This induces tumor cell death in carcinoma cell lines and also prevents tumor growth in animal models. PBD-5,11-dione is a potent inhibitor of survivin transcription and activity, which is an important regulator of apoptosis. It also induces tumor necrosis factor related apoptosis inducing ligand (TRAIL)-mediated apoptosis in tumor cells.
Notice:
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
218.25 g/mol
Formula:
C12H14N2O2
Purity:
Min. 95%
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HS code:
