1-Pyridin-3-ylmethyl-piperazine

CAS: 39244-80-9

Ref. 3D-FP53034

Product Information

• Name: 1-Pyridin-3-ylmethyl-piperazine
• Synonyms: 1-(3-Pyridylmethyl)piperazine, Piperazine, 1-(3-pyridinylmethyl)-

Description

1-Pyridin-3-ylmethyl-piperazine (1PMP) is a synthetic psychoactive substance that can be used as an antidepressant. It has been shown to increase the affinity of chloride ions for diborane, and it has also been shown to be an effective neuroprotective agent. 1PMP is a piperazine derivative, which is chemically similar to piperidine and morpholine. It can be synthesized by reacting borane with 3-chloropyridine. Further reactions with amines or alcohols yield the desired product.
The synthesis of 1PMP can also be achieved by reacting 3-chloropyridine with 2,2-dimethylpropanoyl chloride in the presence of triethylamine and tetrahydrofuran (THF). This reaction may occur in two different ways, yielding either the cis or trans isomers of 1PMP. The cis isomer has been found to have

• Brand: Biosynth

Chemical properties

• Molecular weight: 177.25 g/mol
• Formula: C₁₀H₁₅N₃
• Purity: Min. 95%
• InChI: InChI=1S/C10H15N3/c1-2-10(8-12-3-1)9-13-6-4-11-5-7-13/h1-3,8,11H,4-7,9H2
• InChI key: InChIKey=UNGUQQBXDOAOQO-UHFFFAOYSA-N
• SMILES: c1cncc(CN2CCNCC2)c1