4-Phenoxyaniline

CAS: 139-59-3

Ref. 3D-FP54899

Product Information

• Name: 4-Phenoxyaniline
• Synonyms: 4-Aminophenyl phenyl ether, (4-Aminophenoxy)benzene, 1-Amino-4-phenoxybenzene, 4-(Phenyloxy)aniline, 4-Amino-1-phenoxybenzene, 4-Aminodiphenyl Ether, 4-Phenoxyaniline Hydrochloride (1:1), 4-Phenoxybenzenamine, 4-Phenoxyphenylamine, Aniline, p-phenoxy-, Benzenamine, 4-phenoxy-, NSC 4629, NSC 57084, NSC 61131, p-Aminophenyl phenyl ether, p-Phenoxyaniline, p-Phenoxyphenylamine

Description

4-Phenoxyaniline is a reaction product of aniline and phenol. It has been shown to inhibit the growth of bacteria by binding to the enzyme protein inhibitors. 4-Phenoxyaniline also inhibits the activity of hydrochloric acid, which is used by bacteria for cell division. This drug has been shown to have a high resistance against protonated amines. The high resistance is due to its covalent inhibition with biphenyl and amines. 4-Phenoxyaniline can be used as a potential drug target for the treatment of cancer cells that are resistant to chemotherapy drugs. It has been shown that it can inhibit mitochondrial membrane potential in cancer cells and this may lead to cell death by apoptosis or necrosis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 185.22 g/mol
• Formula: C₁₂H₁₁NO
• Purity: Min. 95%
• InChI: InChI=1S/C12H11NO/c13-10-6-8-12(9-7-10)14-11-4-2-1-3-5-11/h1-9H,13H2
• InChI key: InChIKey=WOYZXEVUWXQVNV-UHFFFAOYSA-N
• SMILES: Nc1ccc(Oc2ccccc2)cc1