4-(Piperazin-1-yl)-1H-indole

CAS: 84807-09-0

Ref. 3D-FP63534

Product Information

• Name: 4-(Piperazin-1-yl)-1H-indole
• Synonyms: 4-(Piperazino)indole, 1-(1H-Indol-4-yl)piperazine, 1-(4-Indolyl)piperazine, 1H-Indole, 4-(1-piperazinyl)-, 4-(1-Piperazinyl)-1H-indole, 4-(piperazin-1-yl)-1H-indole

Description

4-(Piperazin-1-yl)-1H-indole is a compound that is used to study the function of serotonin receptors. It has been shown to have antidepressant-like activity in animal models and has been reported as an analog of 5-HT1A receptor agonists. This compound also has potent dopamine reuptake inhibition, which may be due to its ability to bind to the dopamine transporter in the presynaptic membrane. 4-(Piperazin-1-yl)-1H-indole has been shown to have a pharmacophore with a specific arrangement of functional groups that resemble those found in SSRIs (selective serotonin reuptake inhibitors). Computational methods were used to search for new compounds with similar pharmacological properties.

• Brand: Biosynth

Chemical properties

• Molecular weight: 201.27 g/mol
• Formula: C₁₂H₁₅N₃
• Purity: Min. 95%
• InChI: InChI=1S/C12H15N3/c1-2-11-10(4-5-14-11)12(3-1)15-8-6-13-7-9-15/h1-5,13-14H,6-9H2
• InChI key: InChIKey=YZKSXUIOKWQABW-UHFFFAOYSA-N
• SMILES: c1cc(N2CCNCC2)c2cc[nH]c2c1