Podocarpusflavone A

CAS: 22136-74-9

Ref. 3D-FP74971

Product Information

• Name: Podocarpusflavone A
• Synonyms: Amentoflavone-4'-methyl ether, 4H-1-Benzopyran-4-one, 8-(5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl)-5,7-dihydroxy-2-(4-methoxyphenyl)-
• CAS: 22136-74-9

Description

Podocarpusflavone A is a natural compound that belongs to the class of cyclic nucleotide phosphodiesterase inhibitors. It has been shown in vitro to inhibit cyclic nucleotide phosphodiesterases, which are enzymes that catalyze the hydrolysis of cAMP and cGMP. This inhibition leads to an increase in intracellular calcium concentration and a decrease in camp levels. Podocarpusflavone A has also been shown to have anti-leishmanial activity against Leishmania donovani and Leishmania tropica, but not against Leishmania mexicana or Leishmania braziliensis. Podocarpusflavone A has been found in the genus Podocarpus as well as in other plants such as Isoginkgetin, Ginkgo biloba, and Fructus amomi.

• Brand: Biosynth

Chemical properties

• Molecular weight: 552.48 g/mol
• Formula: C₃₁H₂₀O₁₀
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C31H20O10/c1-39-17-5-2-14(3-6-17)25-13-24(38)30-22(36)11-21(35)28(31(30)41-25)18-8-15(4-7-19(18)33)26-12-23(37)29-20(34)9-16(32)10-27(29)40-26/h2-13,32-36H,1H3
• InChI key: InChIKey=RBTRUVNXLDXHBJ-UHFFFAOYSA-N
• SMILES: COc1ccc(-c2cc(=O)c3c(O)cc(O)c(-c4cc(-c5cc(=O)c6c(O)cc(O)cc6o5)ccc4O)c3o2)cc1